Table 4.
Incidence of Leukocytoclastic Vasculitis in Olmsted County, Minnesota, 1996–2010
| Female Patients | Male Patients | Total | ||||
|---|---|---|---|---|---|---|
| Age at diagnosis, y | No. | Rate (95% CI)a | No. | Rate (95% CI)a | No. | Rate (95% CI)a |
| 0–19 | 6 | 2.2 (0.8–4.8) | 1 | 0.3 (0.0–1.9) | 7 | 1.2 (0.5–2.6) |
| 20–29 | 3 | 2.2 (0.5–6.5) | 6 | 4.7 (1.7–10.2) | 9 | 3.4 (1.6–6.5) |
| 30–39 | 4 | 2.7 (0.7–6.9) | 3 | 2.0 (0.4–5.8) | 7 | 2.3 (0.9–4.8) |
| 40–49 | 10 | 6.7 (3.2–12.3) | 10 | 6.8 (3.3–12.6) | 20 | 6.8 (4.1–10.5) |
| 50–59 | 10 | 8.4 (4.0–15.4) | 7 | 6.2 (2.5–12.7) | 17 | 7.3 (4.3–11.7) |
| 60–69 | 7 | 9.3 (3.7–19.2) | 7 | 10.2 (4.1–21.0) | 14 | 9.7 (5.3–16.3) |
| ≥70 | 3 | 3.1 (0.6–9.1) | 7 | 10.9 (4.4–22.5) | 10 | 6.2 (3.0–11.5) |
| Year of diagnosis | No. | Rate (95% CI)b | No. | Rate (95% CI)b | No. | Rate (95% CI)c |
| 1996–2000 | 13 | 4.4 (2.0–6.8) | 8 | 3.2 (0.9–5.6) | 21 | 3.7 (2.1–5.3) |
| 2001–2005 | 13 | 4.0 (1.8–6.1) | 16 | 5.4 (2.7–8.1) | 29 | 4.6 (2.9–6.3) |
| 2006–2010 | 17 | 4.8 (2.5–7.0) | 17 | 5.3 (2.8–7.9) | 34 | 5.0 (3.3–6.7) |
| LCV subtyped | No. | Rate (95% CI)b | No. | Rate (95% CI)b | No. | Rate (95% CI)c |
| All CSVV | 19 | 1.9 (1.1–2.8) | 19 | 2.3 (1.3–3.4) | 38 | 2.1 (1.4–2.7) |
| Idiopathic CSVV | 16 | 1.6 (0.8–2.4) | 13 | 1.6 (0.7–2.6) | 29 | 1.6 (1.0–2.1) |
| IgA vasculitis | 11 | 1.1 (0.4–1.7) | 14 | 1.6 (0.7–2.4) | 25 | 1.3 (0.8–1.8) |
| Urticarial vasculitis | 9 | 0.9 (0.3–1.5) | 1 | 0.1 (0.0–0.3) | 10 | 0.5 (0.2–0.8) |
| ANCA-associated | 3 | 0.3 (0.0–0.7) | 5 | 0.5 (0.1–1.0) | 8 | 0.4 (0.1–0.7) |
| All patients | 43 | 4.4 (3.1–5.7) | 41 | 4.8 (3.3–6.2) | 84 | 4.5 (3.5–5.4) |
Abbreviations: ANCA, antineutrophil cytoplasmic antibody; CI, confidence interval, CSVV, cutaneous small-vessel vasculitis; LCV, leukocytoclastic vasculitis.
a
Incidence per 100,000 person-years.
b
Incidence per 100,000 person-years age-adjusted to 2000 US white population.
c
Incidence per 100,000 person-years age- and sex-adjusted to 2000 US white population.
d
Age- and sex-adjusted incidence was not calculated for cryoglobulinemic vasculitis because this subgroup included only 3 patients.