Table 5.
Summary of Subtypes and Etiologies of Leukocytoclastic Vasculitis
| Subtype | No. (%) |
|---|---|
| Palpable purpura (predominant) | |
| CSVV (n=38) | |
| Idiopathic | 29 (76) |
| ACTDa | 2 (5) |
| Infectionb | 6 (16) |
| Drug reactionc | 1 (3) |
| IgA vasculitis (n=25) | |
| Idiopathic | 24 (96) |
| Infectiond | 1 (4) |
| ANCA-associated vasculitis (n=8) | |
| Microscopic polyangiitis | 1 (12.5) |
| Granulomatosis with polyangiitis | 2 (25) |
| Eosinophilic granulomatosis with polyangiitis | 2 (25) |
| p-ANCA, NOS | 2 (25) |
| c-ANCA, NOS | 1 (12.5) |
| Cryoglobulinemic vasculitis (n=3) | |
| ACTDe | 1 (33) |
| Infectionf | 2 (67) |
| Urticaria-like lesions | |
| Urticarial vasculitis (n=10) | |
| Normocomplementemic | 8 (80)g |
| Idiopathic | 6 (75) |
| Infectionh | 1(12.5) |
| Drug reactioni | 1 (12.5) |
| Hypocomplementemic | 2 (20) |
| ACTDj | 2 (100) |
Abbreviations: ACTD, autoimmune connective tissue disease; ANCA, antineutrophil cytoplasmic antibody; c-ANCA, cytoplasmic ANCA; CSVV, cutaneous small-vessel vasculitis; NOS, not otherwise specified; p-ANCA, perinuclear ANCA.
a
Sjögren syndrome and systemic lupus erythematosus in 1 patient each.
b
Hepatitis C in 2 patients and hepatitis B and C, parvovirus, pneumonia, and streptococcal infection in 1 patient each.
c
Amoxicillin.
d
Streptococcal infection.
e
Rheumatoid arthritis.
f
Hepatitis C.
g
Complements were not checked in 2 patients.
h
Hepatitis C.
i
Epoetin alfa.
j
Systemic lupus erythematosus and mixed connective tissue disease in 1 patient each.