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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Neurobiol Aging. 2014 Jun 16;35(12):2726–2735. doi: 10.1016/j.neurobiolaging.2014.06.011

Figure 1. Drug administration has no effect on body weight.

Figure 1

(A) Chemical structure of ICI 118,551 (hereafter referred to as ICI), a selective β2AR antagonist. (B) Schematic representation of the treatment paradigm. 8-month-old female 3xTg-AD and NonTg mice were administered 1 mg/kg ICI or 0.9% NaCl (control) via daily i.p. injections for 6 weeks (3xTg-AD mice, n=9/drug group; NonTg mice, n=12/drug group). During the last two weeks of injections, mice were tested in MWM and object recognition tests. (C) Percent weight change throughout the treatment. No statistically significant changes in body weight were detected for any of the groups of mice. Data are presented as means ± SEM.