Table 1.
Time (PI) | Age (months) | Treatment groups (n) | ||
---|---|---|---|---|
P301SBE | PBS | WTBE | ||
1 day | 2 | 5 | 5 | – |
2 weeks | 2.5 | 5 | – | – |
1 month | 3 | 5 | 5 | – |
2 months | 4 | 5 | – | – |
2.5 months | 4.5 | 10a | 5 | 8 |
Mice were unilaterally infused with P301S brain extract (P301SBE), sterile phosphate-buffered saline (PBS) or wild-type brain extract (WTBE), and were aged to pre-defined time points
PI post-infusion
a5 mice used for biochemistry