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Impact of immunization on survival following DENV-4 virus challenge. Groups of 15 AG129 mice were immunized with a single dose of TDV-4, TDV-2 or TDV vaccines. Control animals were immunized with FTA (virus diluents). On day 60 post-primary immunization animals were challenged with mouse adapted DENV-4 and morbidity and mortality was monitored over a period of four weeks.
