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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Respir Physiol Neurobiol. 2014 Sep 19;0:147–159. doi: 10.1016/j.resp.2014.09.006

Figure 3.

Figure 3

Total changes in frequency of breathing (Freq), Rejection Index (Rinx) and Rejection Index/frequency (Rinx/freq) in C57BL6 mice before, during the first minute (Gas – 1 min) and for the entire 5 min (Gas – 5 min) challenge with a hypoxic (HX) gas mixture (10% O2, 90% N2), a hypercapnic (HC) mixture (5% CO2, 21% O2, 74% N2), or a hypoxic-hypercapnic (H-H) mixture (5% CO2, 10% O2, 85% N2), and upon return to room-air (15 min total). The data are mean ± SEM. There were 16 mice in each group. *P < 0.05, significant response. †P < 0.05, HC or HH versus HX.