Table 1b. Maternal Outcomes in Randomized Controlled Trials - Glyburide.
| Author Ref | Drug | Preeclampsia | PIH | Cesarean Delivery | Preterm Delivery | |
|---|---|---|---|---|---|---|
| Langer et al.3 | Glyburide (n=201) |
6 | ND | 23 | ND | |
| Insulin (n=203) |
6 | ND | 24 | ND | ||
|
| ||||||
| Bertini et al.12 | Glyburide (n=24) |
ND | ND | 50 | 0 | |
| Insulin (n=27) |
ND | ND | 44 | 0 | ||
| Acarbose (n=19) |
ND | ND | 52 | 0 | ||
|
| ||||||
| Moore et al.27a | Glyburide (n=74) |
4 | ND | 3** | ND | |
| Metformin (n=75) |
3 | ND | 15 | ND | ||
|
| ||||||
| Silva et al.40 | Glyburide (n=96) |
ND | ND | 68 | 4 | |
| Metformin (n=104) |
ND | ND | 66 | 5 | ||
Data is presented as %.
PIH: Pregnancy-Induced Hypertension; ND: Not Determined; Preterm delivery defined as birth < 37 weeks;
**
P < 0.05 compared with metformin
a
Percentage of non-elective cesarean delivery.