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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Semin Perinatol. 2014 Oct 12;38(8):508–515. doi: 10.1053/j.semperi.2014.08.012

Table 1b. Maternal Outcomes in Randomized Controlled Trials - Glyburide.

Author Ref Drug Preeclampsia PIH Cesarean Delivery Preterm Delivery
Langer et al.3 Glyburide
(n=201)
6 ND 23 ND
Insulin
(n=203)
6 ND 24 ND

Bertini et al.12 Glyburide
(n=24)
ND ND 50 0
Insulin
(n=27)
ND ND 44 0
Acarbose
(n=19)
ND ND 52 0

Moore et al.27a Glyburide
(n=74)
4 ND 3** ND
Metformin
(n=75)
3 ND 15 ND

Silva et al.40 Glyburide
(n=96)
ND ND 68 4
Metformin
(n=104)
ND ND 66 5

Data is presented as %.

PIH: Pregnancy-Induced Hypertension; ND: Not Determined; Preterm delivery defined as birth < 37 weeks;

**

P < 0.05 compared with metformin

a

Percentage of non-elective cesarean delivery.