Table 2. SNP analysis.

Table 2 lists p-values for the comparisons of SNP genotype and ELS with each of the DASS components. RAW lists the unadjusted p-values from either the test of SNP genotype against DASS score (MAIN EFFECTS) or the unadjusted p-values from a linear test of whether early life stress (ELS) significantly interacted with the SNP genotype and DASS phenotype relationship (ELS INTERACTION). SNP ADJUSTED are the p-values adjusted for testing 58 variants using the bootstrap procedures in Plink. CORRECTED corrects the SNP ADJUSTED p-values for the 3 different DASS score tests using a Bonferroni correction. Only significant SNPs are shown.

ANXIETY
MAIN EFFECTS							ELS INTERACTION
SNP	RAW	SNP ADJUSTED	CORRECTED		FREQ	HWE	SNP	RAW	SNP ADJUSTED	CORRECTED		FREQ	HWE
rs237886	0.028	0.036		0.107	0.444	0.979	rs59190448	0.022	0.019		0.058	0.190	0.018
							rs139832701	0.051	0.023		0.068	0.016	1.000
							rs17297971	0.011	0.333	N/A		0.047	0.460
							rs237924	0.036	0.438	N/A		0.062	0.142
							rs7652281	0.045	0.857	N/A		0.062	0.142

STRESS
MAIN EFFECTS							ELS INTERACTION
SNP	RAW	SNP ADJUSTED	CORRECTED		FREQ	HWE	SNP	RAW	SNP ADJUSTED	CORRECTED		FREQ	HWE
rs11131147	0.014	0.016		0.047	0.068	0.815	rs139832701	0.007	0.005		0.016	0.015	1.000
rs7652281	0.038	0.049		0.148	0.062	0.142	rs7652281	0.016	0.857	N/A		0.062	0.142
rs237892	0.054	0.065	N/A		0.071	0.059	rs237892	0.029	0.356	N/A		0.071	0.059
							rs190216	0.035	0.214	N/A		0.079	0.025

DEPRESSION
MAIN EFFECTS							ELS INTERACTION
SNP	RAW	SNP ADJUSTED	CORRECTED		FREQ	HWE	SNP	RAW	SNP ADJUSTED	CORRECTED		FREQ	HWE
rs139832701	0.004	0.010		0.011	0.015	1.000	rs139832701	0.001	0.004		0.011	0.015	1.000
rs11131147	0.015	0.019		0.058	0.068	0.815
rs13093809	0.035	0.049		0.147	0.047	0.437