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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Osteoarthritis Cartilage. 2014 Jul 18;22(11):1861–1868. doi: 10.1016/j.joca.2014.07.003

Figure 1.

Figure 1

Uterus weights (A) of 49-day-old, and Body weights (B) of 21- and 49-day-old female WT and ER beta KO that were either sham-operated or ovariectomized and treated with placebo or estradiol (10 nanogram/gram body weight/day) for 4 weeks. n= 12–13 mice for each age, genotype and treatment. Values are the means with lower and upper limits of 95% CI. * = significant difference between Sham and OVX-placebo groups. #= significant difference between OVX-placebo and OVX-estradiol groups. In (A) WT, * p=0.004, # p=0.007; ER-beta KO, *and # p<0.001. In (B) WT, * p=0.005, # p=0.024; ER-beta KO, * p<0.001, # p=0.004.