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Col2 Immunohistochemistry (A) and Safranin O staining (B) were performed on the mandibular condyles of 49-day-old female sham-operated or ovariectomized WT and ERβ KO mice treated with placebo or estradiol. In (A), the cartilage area was demarcated with black dashed line. All images were taken under 10X magnification. Bars= 100μm.
