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. 2014 Nov 25;14:621. doi: 10.1186/s12879-014-0621-1

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© Bernin et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Serum cytokine and chemokine levels in individuals infected withE. histolyticaorE. dispar. The sera were from 34 patients with amebic liver abscess (ALA), 41 asymptomatic E. histolytica carriers (AC), and 24 individuals infected with the apathogenic E. dispar. Cytometric bead array analyses were used to determine the serum concentrations of IL-4, IL-10, IL-6, IL-1β, chemokine (C-C motif) ligand 2 (CCL2), and CCL3 in the sera from ALA patients, AC, and E. dispar-infected subjects (A–F). Statistics: Kruskal-Wallis test followed by Mann–Whitney U test with Bonferroni's correction (*p < 0.05, **p < 0.005, and ***p < 0.0001); ns, not significant. ALA, amebic liver abscess; AC, asymptomatic E. histolytica carrier; E. dispar, individuals infected with E. dispar.