Table 4.
Signaling pathways significantly upregulated at 28 days post-infection
| Pathway Name | Enrichment ratio 1 | Adjusted p value 2 |
|---|---|---|
| Amino Acid Metabolism | 16.26 | 7.79e-15 |
| Complement and Coagulation Cascades | 21.56 | 1.66e-12 |
| Adipogenesis | 12.17 | 1.18e-11 |
| Type II interferon signaling (IFN-γ) | 17.77 | 1.18e-11 |
| Chemokine signaling pathway | 9.25 | 1.46e-10 |
| Blood clotting cascade | 39.54 | 2.74e-10 |
| Toll-like receptor signaling pathway | 11.04 | 1.69e-08 |
| Cytokines and inflammatory Response (BioCarta) | 12.47 | 6.10e-07 |
| IL-4 signaling pathway | 12.14 | 6.89e-07 |
| IL-2 Signaling pathway | 9.90 | 3.38e-06 |
1Ratio of the number of genes in the gene set to the expected number in the category based on the human database.
2 p value adjusted by the multiple test adjustment.