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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Am J Obstet Gynecol. 2014 Jun 19;211(6):627.e1–627.e9. doi: 10.1016/j.ajog.2014.06.036

TABLE 3.

Impact of comorbid conditions on survival in women who were diagnosed with endometrial cancer

Variable White women
Black women
P interaction
Hazard ratioa 95% confidence interval P value Hazard ratioa 95% confidence interval P value
Death from any cause

 Diabetes mellitus 1.63 1.13–2.35 .009 1.17 0.80–1.71 .429 .302

 Hypertension 0.96 0.70–1.32 .817 0.52 0.34–0.79 .003 .008

 Obesity (body mass index, ≥30 kg/m2) 1.04 0.75–1.43 .820 1.04 0.69–1.56 .865 .670

 Morbid obesity (body mass index, ≥40 kg/m2) 1.33 0.86–2.06 .198 1.07 0.70–1.63 .771 .901

 Charlson comorbidity score .991

  1 1.89 1.24–2.90 .003 1.07 0.66–1.72 .795

  ≥2 1.71 1.17–2.50 .006 2.28 1.46–3.56 < .001

Death from endometrial cancer

 Diabetes mellitus 1.00 0.40–2.49 .999 0.71 0.36–1.37 .302 .978

 Hypertension 0.47 0.23–0.98 .044 0.35 0.19–0.67 .001 .740

 Obesity (body mass index, ≥30 kg/m2) 0.89 0.44–1.79 .739 0.81 0.44–1.51 .510 .723

 Morbid obesity (body mass index, ≥40 kg/m2) 0.72 0.24–2.15 .557 1.04 0.53–2.02 .913 .760

 Charlson comorbidity score .312

  1 2.74 1.16–6.48 .022 1.10 0.51–2.36 .806

  ≥2 0.92 0.35–2.41 .864 1.97 0.98–3.98 .059
a

Adjusted for year and age at diagnosis, Federation of International Gynecologists and Obstetricians stage, grade, histologic type, receipt of surgery, chemotherapy, and radiation therapy.

Ruterbusch. Race, comorbidities, and endometrial cancer survival. Am J Obstet Gynecol 2014.