Table I.
Patient Characteristics
| Uninterrupted Warfarin (n = 276) | Dabigatran (n = 374) | Bridged (n = 232) | P Value | |
|---|---|---|---|---|
| Age (years) | 62 ± 11 | 61 ± 12 | 61 ± 11 | 0.14 |
| Male | 178 (64.5%) | 266 (71.1%) | 160 (69.0%) | 0.19 |
| BMI | 31 ± 6 | 29 ± 6 | 31 ± 6 | 0.024 |
| Diabetes | 56 (20.3%) | 45 (12.0%) | 39 (16.8%) | 0.016 |
| Hypertension | 183 (66.3%) | 214 (57.2%) | 158 (68.1%) | 0.010 |
| CHF | 54 (19.6%) | 38 (10.2%) | 27 (11.6%) | 0.002 |
| History of stroke/TIA | 22 (7.9%) | 39 (10.4%) | 17 (7.3%) | 0.49 |
| CAD | 51 (18.5%) | 58 (15.5%) | 48 (20.7%) | 0.25 |
| Prior MI | 16 (5.8%) | 16 (4.3%) | 8 (3.4%) | 0.43 |
| LVEF (%) | 55 ± 11 | 56 ± 10 | 55 ± 9 | 0.21 |
| LA dimension (mm) | 46 ± 10 | 45 ± 9 | 42 ± 6 | <0.001 |
| Type of AF | 0.19 | |||
| Paroxysmal | 174 (63.0%) | 208 (55.6%) | 130 (56.0%) | 0.190 |
| Persistent | 98 (35.5%) | 156 (41.7%) | 93 (40.1%) | 0.190 |
| Longstanding persistent | 4 (1.5%) | 10 (2.7%) | 9 (3.9%) | 0.190 |
| CHADS2 score | 1.4 ± 1.4 | 1.1 ± 1.1 | 1.2 ± 1.1 | <0.001 |
| HASBLED Score | 2.1 ± 1.5 | 2.2 ± 1.3 | 2.8 ± 1.0 | <0.0001 |
Boldface indicates statistically significance. AF = atrial fibrillation; BMI = body mass index; CAD = coronary artery disease; CHF = congestive heart failure; LA = left atrial; LVEF = left ventricular ejection fraction; MI = myocardial infarction; TIA = transient ischemic attack.