Fig. 1.
(A–E) Photomicrographs. (A and B): Gross photographs of heart from young man dying suddenly while playing basketball. (A) Cross-section of ventricles showing scars in papillary muscles (PM) and subepicardium (SE) with normal coronary artery characteristic of sarcoid lesions as opposed to ischemic injury. (B) Right ventricular outflow tract from same patient showing scarring below the pulmonary valve (S) and a granuloma in the pulmonary artery (arrow). (C) Histologic section of left ventricular lesion showing typical discrete, well-circumscribed nonnecrotizing granulomas (G) typical of sarcoidosis (hematoxylin and eosin [H&E] stain, ×40). (D) High magnification showing typical giant cells with numerous nuclei (H&E stain, ×400). (E) Endomyocardial biopsy from patient resuscitated from sudden cardiac death, showing nonnecrotizing granuloma (NNG) typical of sarcoidosis (H&E stain, ×200).