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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Semin Cell Dev Biol. 2014 Sep 28;0:204–212. doi: 10.1016/j.semcdb.2014.09.022

Figure 5. Tight junction proteins display distinct dynamic behaviors.

Figure 5

A. Occludin diffuses passively within tight junction (TJ) and lateral membrane pools. Consistent with this, fluorescence recovery begins peripherally when a large area of the tight junction is bleached. B. Part of tight junction-associated ZO-1 exchanges by an active, energy-dependent process with a large cytosolic pool. Consistent with this, fluorescence recovery occurs uniformly across a large bleached tight junction region. From Shen et al. J Cell Biol. 2008.