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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Alzheimers Dement. 2014 Jul 14;10(6):735–742.e4. doi: 10.1016/j.jalz.2014.04.520

Figure 3.

Figure 3

Sigmoid fits for the cognitive markers as a function of the estimated ADPS (top), and the 90% confidence intervals for the inflection points (bottom). The horizontal axis represents the ADPS estimated for each subject. The probabilities of having a certain ADPS conditioned on cognitive status are reflected by the gray and green shaded areas, with gray corresponding to the probabilities associated with the CN individuals and green corresponding to CI. Although we provide confidence intervals around inflection point estimates, statistical significance of their temporal ordering was based on permutation tests. ADPS = Alzheimer’s Disease Progression Score; CVLT = California Verbal Learning Test; CVLT-sum = CVLT immediate recall; CVLT-frs = CVLT short delayed free recall; CVLT-frl = CVLT long delayed free recall; BVRT = Benton Visual Retention Test error score; BMS = Blessed Information Memory Concentration score; MMSE = Mini-Mental State Exam.