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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Gastroenterology. 2014 Aug 30;147(6):1393–1404. doi: 10.1053/j.gastro.2014.08.039

Figure 1. CSC markers in human HCC.

Figure 1

(A) Flow cytometry analysis of putative CSC markers in primary HCC tumors (n=17 patients, mean±SEM). Results are percentage marker positive population in 7-AAD−CD45− (viable non-immune) cells. CD44+ percent was significantly higher than other markers (p < 0.05).

(B) Representative HCC patient FACS in (A).

(C) Representative patient-derived HCC xenografts FACS (n=3 patients) gated on mCD45−H2Kd− to exclude murine infiltrating cells.

(D) Representative FACS for CSC markers in HCC cell lines.

Results are the percentage positive population in viable cells relative to negative isotype controls.