Table 2.

Intention-to-treat analyses

	Treatment (20 mL/kg 0.9% NaCl)	Control (observation alone)	Treatment difference and 95% CI of the difference	P-value
Primary end-point (mean [SD] minutes)	(n = 73)	(n = 71)
EDLOS	287 (171)	274 (131)	14 (−37 to 63)	0.89
Secondary end-points
Treatment time	244 (143)	232 (116)	12 (−31 to 55)	0.94
Observational Assessment of Alcohol Intoxication (OAAI)	(n = 61)	(n = 54)
Absolute change of total OAAI score at 2 h	−10 (9)	−7 (8)	−3 (−6 to 1)	0.16
Per cent change of total OAAI score at 2 h	−40 (33)	−33 (44)	−7 (−21 to 7)	0.34
Rate of change of total OAAI score (points/h) at 2 h	−4.8 (4.8)	−3.6 (4.2)	−1.2 (−3.0 to 0.6)	0.16
Rate of change of total OAAI score (points/h) at discharge	−3.6 (3.0)	−4.2 (3.0)	0.6 (−0.6 to 2.4)	0.31
Breath alcohol level (% alcohol)	(n = 43)	(n = 44)
Absolute change of BAL at 2 h	−0.036 (0.03)	−0.013 (0.1)	−0.023 (−0.06 to 0.01)	0.16
Per cent change of BAL at 2 h	−19 (14)	−8 (69)	−11 (−33 to 10)	0.74
Rate of change (%/h) of BAL at 2 h	−0.02 (0.01)	−0.01 (0.05)	−0.01 (−0.03 to 0.01)	0.16
Rate of change (%/h) of BAL at discharge	−0.01 (0.04)	−0.02 (0.02)	0.01 (−0.01 to 0.03)	0.82

Values are means (SD) unless stated otherwise. Where the measurements were not normally distributed, a Mann–Whitney U-test was used instead of an independent sample t-test. BAL, breath alcohol level; CI, confidence interval; EDLOS, emergency department length of stay; NaCl, sodium chloride solution; treatment difference: treatment minus control.¹⁰