Table 2.
Main procedure-related adverse events in the elderly (≥70 years) and younger patients (<70 years) in the first 3 months post-treatment by severity (CTCAE v3)
| CTCAE | CTCAE v3: number (%) of patients |
P-value between sub-groups | ||||
|---|---|---|---|---|---|---|
| Study sub-group | All Grades | Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
| Fatigue | ||||||
| Age ≥ 70 years | 10 (22.7%) | 8 (18.1%) | 1 (2.3%) | 1 (2.3%) | – | |
| Age <70 years | 15 (23.8%) | 12 (19.0%) | 2 (3.2%) | 1 (1.6%) | – | |
| Abdominal pain | ||||||
| Age ≥ 70 yearsr | 7 (15.9%) | 6 (13.6%) | 1 (2.3%) | – | – | |
| Age < 70 yearsr | 12 (19.0%) | 9 (14.3%) | 2 (3.2%) | 1 (1.5%) | – | |
| Nausea and/or vomiting | ||||||
| Age ≥ 70 years | 12 (27.3%) | 9 (20.5%) | 2 (4.5%) | 1 (2.3%) | – | |
| Age < 70 years | 20 (31.7%) | 16 (25.4%) | 4 (6.3%) | – | – | |
| Fever | ||||||
| Age ≥ 70 years | 5 (11.4%) | 4 (9.0%) | 1 (2.4%) | – | – | |
| Age <70 years | 6 (9.5%) | 5 (7.9%) | 1 (1.6%) | – | – | |
| Peak total bilirubina | ||||||
| Age ≥ 70 years | 11 (29.7%) | 7 (18.9%) | – | 3 (8.1%) | 1 (2.7%) | |
| Age < 70 years | 15 (26.8%) | 9 (16.0%) | 3 (5.4%) | 2 (3.6%) | 1 (1.8%) | |
CTCAE v3: Common Terminology Criteria for Adverse Events version 3.0.
a
Percentages calculated based on available data.