Table 1.
Demographic and clinical features of the sample by diagnosis and sex.
| HC-M (n=20) |
HC-F (n=32) |
MDD-M (n=20) |
MDD-F (n=32) |
|
|---|---|---|---|---|
| Age | 14.7±1.2 | 15.1±1.6 | 15.3±1.6 | 15.0±1.5 |
| Tanner scores | 4.2 ±0.7 | 4.4±0.5 | 4.4±0.7 | 4.4±0.6 |
| FGAS | 91.0±8.1 | 89.9±6.2 | 66.1±13.0 | 64.4±11.7 |
| CGAS | 92.2 ±5.8 | 91.0±4.0 | 51.3±5.6 | 53.4±5.2 |
| CDRS-R* | 18.0±1.3 | 18.5±1.6 | 55.7±7.4 | 56.5±10.1 |
| Age of onset | – | – | 13.4±2.9 | 12.9±2.6 |
| Length of current depressive episode° | – | – | 16.0±26.7 | 20.2±21.8 |
| Family history of MDD (n) | – | – | 13 | 27 |
| Comorbid psychiatric diagnosis (n) | – | – | 6 | 15 |
| ADHD | – | – | 3 | 6 |
| Generalized anxiety | – | – | 3 | 4 |
| Phobias | – | – | – | 2 |
| Oppositional defiant dis. | – | – | – | 5 |
| OCD | – | – | – | 2 |
*Missing data n=31 for MDD females.
°In months.
HC, healthy control; MDD, major depressive disorder; M, males; F, females; FGAS, family global assessment scale; CGAS, clinical global assessment scale; CDRS-R, children’s depression rating scale - revised; ADHD, attention deficit hyperactivity disorder; OCD, obsessive compulsive disorder.