Table 2. Distribution of KRAS mutations by tumor type.
KRAS Mutation | CRC* (%) | Lung (%) | Pancreatic (%) | Other (%) | Total |
---|---|---|---|---|---|
G12D | 68 (31) | 8 (17) | 12 (43) | 18 (26) | 106 (29) |
G12V | 51 (23) | 10 (21) | 6 (21) | 13 (19) | 80 (22) |
G12C | 13 (6) | 19 (40) | 0 | 9 (13) | 41 (11) |
G13D | 29 (13) | 2 (4) | 0 | 9 (13) | 40 (11) |
G12A | 15 (7) | 4 (8) | 0 | 6 (9) | 25 (7) |
G12S | 14 (7) | 1 (2) | 0 | 0 | 15 (4) |
Q61H | 6 (3) | 2 (4) | 1 (4) | 5 (7) | 14 (4) |
G13C | 2 (1) | 1 (2) | 0 | 1 (1) | 4 (1) |
Other | 16 (7) | 0 | 8 (29) | 7 (10) | 40 (11) |
Unknown | 7(3) | 1 (2) | 1 (4) | 0 | 9 (2) |
Total | 221 | 48 | 28 | 68 | 365 |
Colorectal cancer