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. 2014 Aug 21;5(19):9092–9105. doi: 10.18632/oncotarget.2377

Figure 3. LGR5 promotes the proliferation of cervical cancer cells by accelerating the cell cycle.

Figure 3

(A) The effect of LGR5 on the proliferation of HeLa cells. (B) The effect of LGR5 on the viability of HeLa cells. (C) The effect of LGR5 on the proliferation of SiHa cells. (D) The effect of LGR5 on the viability of SiHa cells. (E) The cell cycle of LGR5-modulated HeLa cells was analyzed by flow cytometry. (F) The effect of LGR5 on the cell cycle of HeLa cells. (G) The cell cycle of LGR5-modulated SiHa cells was analyzed by flow cytometry. (H) The effect of LGR5 on the cell cycle of SiHa cells. shLGR5: shRNA for LGR5, shCtr: shRNA for control, GFP: green fluorescent protein. Values are shown as the mean±SD collected from three experiments in duplicate. One-Way ANOVA was performed and * p<0.05, ** p<0.01 vs. control.