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. 2014 Sep 5;5(19):9382–9395. doi: 10.18632/oncotarget.2412

Figure 2. LIMK is of prognostic value.

Figure 2

(A) Patients with low LIMK1 in all glioma have a better overall survival at the RNA level (<2 fold compared to normal brain) in the REMBRANDT glioma data set. (B) Patients with low LIMK2 in all glioma have a better overall survival at the RNA level (<2 fold compared to normal brain) in the REMBRANDT glioma data set. (C&D) At the Copy Number Level, Patients with high LIMK1 but not LIMK2 (>3 copies compared to normal brain) have poor survival in GBM patients. (E&F) Using the TCGA data set for 162 samples with subtype information, LIMK1 and LIMK2 are not differentially expressed in GBM subtypes. *p<0.05, **p<0.01.