Table 1. Correlation between CTHRC1 expression and clinicopathologic characteristics of NSCLC.
Characteristics | CTHRC1 expression | Chi-square test | |
---|---|---|---|
High expression | Low expression | p-value | |
Normal lung tissues | 6 | 66 | <0.001 |
NSCLC tissues | 212 | 80 | |
Age(years) | 0.584 | ||
≤ 50 | 68 | 23 | |
> 50 | 144 | 57 | |
Gender | 0.282 | ||
Male | 151 | 62 | |
Female | 61 | 18 | |
Smoking | <0.001 | ||
Yes | 168 | 21 | |
No | 44 | 59 | |
Clinical stage | <0.001 | ||
I | 20 | 33 | |
II | 102 | 41 | |
III | 52 | 5 | |
IV | 38 | 1 | |
T Classification | <0.001 | ||
T1 | 62 | 45 | |
T2 | 74 | 21 | |
T3 | 57 | 12 | |
T4 | 19 | 2 | |
N Classification | 0.097 | ||
N0 | 106 | 53 | |
N1 | 78 | 20 | |
N2 | 15 | 4 | |
N3 | 13 | 3 | |
Lymph node metastasis | 0.013 | ||
N0 | 106 | 53 | |
N1-3 | 106 | 27 | |
M Classification | <0.001 | ||
M0 | 174 | 79 | |
M1 | 38 | 1 | |
EGFR mutation | 0.562 | ||
Positive | 29 | 17 | |
Negative | 35 | 16 | |
K-ras mutation | 0.711 | ||
Positive | 9 | 5 | |
Negative | 49 | 34 |