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. 2014 Sep 9;5(19):9514–9529. doi: 10.18632/oncotarget.2413

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Copyright: © 2014 Wei et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

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(A) Heatmap of hierarchical clustering of 1,475 genes differentially expressed (fold change >1.5) in fusion progeny compared to parental cancer cell (green, down-regulated; red, up-regulated). Transcription profiles were from two independent cultures of H441 cells, and passages 20 and 50 of fusion progeny. Functional annotations of up-regulated (B) or down-regulated (C) genes in fusion progeny compared to H441 cells. Genes were classified into Gene Ontology biological process categories using DAVID bioinformatics resources. P values for gene-enrichment were calculated using a modified Fisher exact (EASE) score and listed behind each column.