Skip to main content
. 2014 Oct 27;171(22):4981–5010. doi: 10.1111/bph.12848

Table 11.

Examples of PAD inhibitors

Inhibitor Structure Potency (µM) PAD selectivity Reference
Cl-amidine Inline graphic 5.9 Pan-PAD (Luo et al., 2006)
o-F-amidine Inline graphic 21.6 PAD4 (Knuckley et al., 2010a; Causey et al., 2011)
TDFA Inline graphic 2.3 PAD4 (Jones et al., 2012)
Streptonigrin Inline graphic 1.87 PAD4 (Knuckley et al., 2010b)