| TARGETS | LIGANDS | ||
|---|---|---|---|
| C5a receptor | All trans-retinoic acid (ATRA), tretinoin | IL-6 | PAF, platelet activating factor |
| Caspase | Atorvastatin | IL-8 (CXCL8) | PMX53 |
| CXCL2 | C5a complement | IL-10 | Simvastatin |
| CXCR2 | Cathelicidin LL-37 | IL-12 | TNFα |
| ER-β, oestrogen receptor β | Chloroquine | IL-33 | |
| Haem oxygenase 1 | Curcumin | LPS | |
| HMG-CoA reductase | DHEA, dehydroepiandrosterone | Metyrapone | |
| NOS | Eritoran | Mifepristone (RU486) | |
| TLR4, Toll-like receptor 4 | IL-1β | PACAP, pituitary adenylate cyclase-activating polypeptide |
This Table lists key protein targets and ligands in this article which are hyperlinked to corresponding entries in http://www.guidetopharmacology.org, the common portal for data from the IUPHAR/BPS Guide to PHARMACOLOGY (Pawson et al., 2014) and are permanently archived in the Concise Guide to PHARMACOLOGY 2013/14 (Alexander et al., 2013a,b,c,d).