. 2014 Oct 15;592(Pt 21):4789–4802. doi: 10.1113/jphysiol.2014.278846

Table 3.

Haemodynamic responses to sympathetic stimulation at rest and during muscle contraction.

			2 Hz		5 Hz
Muscle contractile state	Group	Drug condition	FBF (ml min⁻¹)	FVC (ml min⁻¹ mmHg⁻¹)	FBF (ml min⁻¹)	FVC (ml min⁻¹ mmHg⁻¹)
Rest	Sedentary	Control	−0.6 ± 0.2	−0.008 ± 0.002	−0.8 ± 0.3	−0.011 ± 0.003
		SMTC	−0.8 ± 0.3	−0.008 ± 0.002	−1.1 ± 0.4	−0.012 ± 0.003
		SMTC + l-NAME	−0.9 ± 0.3	−0.009 ± 0.003	−1.1 ± 0.4	−0.011 ± 0.004
	Exercise trained	Control	−0.9 ± 1.0	−0.010 ± 0.001	−1.3 ± 0.2	−0.015 ± 0.003
		SMTC	−1.0 ± 0.3	−0.010 ± 0.002	−1.6 ± 0.4	−0.015 ± 0.004
		SMTC + l-NAME	−1.2 ± 0.4	−0.009 ± 0.002	−1.5 ± 0.6	−0.012 ± 0.004
Contraction	Sedentary	Control	−0.5 ± 0.6	−0.006 ± 0.005^‡	−1.1 ± 1.2	−0.016 ± 0.008
		SMTC	−1.1 ± 0.8^§	−0.014 ± 0.004^‡^§	−1.7 ± 1.3^§	−0.024 ± 0.007^*^§
		SMTC + l-NAME	−1.8 ± 1.0^*†^§	−0.018 ± 0.005^‡^§	−2.4 ± 1.3^*^§	−0.026 ± 0.007^*^§
	Exercise trained	Control	−0.7 ± 0.4	−0.010 ± 0.004	−1.2 ± 0.6^‡	−0.018 ± 0.004
		SMTC	−2.4 ± 0.6^*^§	−0.025 ± 0.005^*^§	−3.3 ± 0.6^‡^§	−0.036 ± 0.006^*^§
		SMTC + l-NAME	−2.7 ± 0.8^*^§	−0.024 ± 0.006^*^§	−4.0 ± 1.0^‡^§	−0.036 ± 0.006^*^§

Values are means ± s.d. Abbreviations: FBF, femoral blood flow; FVC, femoral vascular conductance; HR, heart rate; MAP, mean arterial blood pressure; l-NAME, N_ω-nitro-l-arginine methyl ester; SMTC, S-methyl-l-thiocitrulline. ^*Statistically significant difference from control conditions within the specified contractile state. ^†Statistically significant difference from SMTC condition within the specified contractile state. ^‡Statistically significant difference between all drug conditions within the specified contractile state. ^§Statistically significant difference between groups within specified drug condition and contractile state. P < 0.05 was considered statistically significant.