Skip to main content
. 2014 Nov 10;143(4):550–559. doi: 10.1111/imm.12333

Figure 1.

Figure 1

Marginal zone B-cell population at the periphery was increased in B-cell-specific NICD1 expressing mice. (a) Flow cytometric analyses of surface markers of B-cell lineage development of bone marrow cells from Cd19Cre/+, Cd19Cre/+ Notch1flox/flox and Cd19Cre/+ R26NICD1 mice. (b) Flow cytometric analyses of surface markers of T-cell and B-cell populations of total cells from spleens and lymph node of Cd19Cre/+, Cd19Cre/+ Notch1flox/flox and Cd19Cre/+ R26NICD1 mice. (c) Flow cytometric analyses of surface markers of the B-cell subpopulation in spleen of Cd19Cre/+, Cd19Cre/+ Notch1flox/flox and Cd19Cre/+ R26NICD1 mice. (d) The number of each B-cell population in the bone marrows and spleens of Cd19Cre/+, Cd19Cre/+ Notch1flox/flox and Cd19Cre/+ R26NICD1 mice (n = 5 mice) is presented as mean ± SD. Mann–Whitney U-test: *P < 0·05.