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Prenatal dexamethasone (DEX) treatment decreased histone deacetylase (HDAC) but not histone acetyltransferase (HAT) activity of rat spleen at the long-term stage. Bar graphs showing (a) HAT activity and (b) HDAC activity of prenatal DEX group relative to vehicle. Results were expressed as fold difference over vehicle (mean ± SEM; *P < 0·05; n = 6).
