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. 2014 Nov 10;143(4):670–678. doi: 10.1111/imm.12350

Figure 1.

Figure 1

A20 expression increased in myeloid dendritic cells (mDCs) isolated from patients chronically infected with hepatitis C virus (HCV) compared with healthy subjects and is decreased in mDCs isolated from HCV patients receiving antiviral therapy. (a) Quantitative real-time PCR was used to detect A20 mRNA levels in mDCs isolated from treatment-naive patients (n = 31), patients receiving antiviral treatment (n = 16), patients achieving sustained virological responses (n = 10) and healthy subjects (n = 15). Each symbol represents an individual subject, and the horizontal bars represent the median values. (b, c) A20 expression in mDCs was assessed by flow cytometry. Corresponding changes in % gated and mean fluorescence intensity (MFI) are shown with isotype control in representative histograms (b). Summary data of corresponding changes in MFI from subjects from the four groups are shown by bar figure (c). *P < 0·05, **P < 0·05, ***P < 0·001, ns: not significant.