A20 expression was negatively correlated with the expression of HLA-DR, CD86, CCR7 and interleukin-12 (IL-12), but positively correlated with IL-10 production. Immunophenotype molecules HLA-DR, CD86, CCR7 and cytokines IL-12, IL-10 in myeloid dendritic cells isolated from treatment-naive patients and activated with poly-I:C in the presence or absence of interferon-α were detected and their correlations with A20 were analysed by Spearman’s correlation analysis with two-tailed significance denoted in the upper right corner of each analysis. **P < 0·01, ***P < 0·001.