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. 2014 Sep 17;33(20):2363–2373. doi: 10.15252/embj.201488784

Figure 3. Specific temporal activation of Notch signaling is sufficient to rescue HSPCs in notch3 morphants.

Figure 3

A, B WISH for runx1 in 26 hpf hsp70:gal4; UAS:NICD-myc uninjected or notch3 morphant transgenic embryos with heat-shock induction at 14 hpf (A) or 20 hpf (B), with or without enforced NICD expression. Arrowheads indicate the presence or absence of HSPCs at the midline.

C Quantitation of results recording percentages of embryos displaying normal or decreased numbers of runx1+ HSPCs at 26 hpf in notch3 morphants with heat-shock induction conditions.