Table 3.

Characteristics of Hematopoietic Stem Cell Grafts and Outcome of HSCT

Donor	Patient	Cell Source	HLA Match	Composition of Donor Graft		Infections Post HSCT	GVHD		Outcome
				CD34+ × 106/kg	CD3+ × 106/kg		Acute	Chronic *
MRD
	1	PBSC	10/10	7.0	247	CRBSI	Gr. II skin, liver	Severe	Alive 4.7y
	2	PBSC	10/10	4.1	380	IFI, CMV viremia, BSI	Gr IV skin, liver	N/A	Died day 90 - sepsis, GVHD
	3	PBSC	10/10	6.0	174	-	Gr II skin, gut	-	Alive 3.2y Relapsed 1.4y, now 1.8y post HSCT #2
	4	PBSC	10/10	6.4	330	-	-	Mild	Alive at 2.3y
URD
	5	PBSC	10/10	6.87	354	-	-	-	Alive 4.5y
	6	PBSC	10/10	8.25	207	-	Gr III skin, gut, liver	Mild	Alive 3.5y
	7	PBSC	9/10	7.25	447	-	-	-	Alive 2.3y
	8	PBSC	10/10	6.3	188	CMV, IFI	Gr IV skin, gut, liver	-	Rejected 10m, retransplanted, died at 1.5y
UCB
	9	Single UC	4/6	0.78	3.48	CRBSI, IFI, CMV-viremia	-	-	Developed donor cell AML 2.5y post HSCT and died at 3y
	10	Double UC1	4/6	0.18	5.04	FN, endocarditis	Gr.I-II skin, gut	-	Alive 3.4y
		UC2	4/6	0.65	10.5
	11	Double UC1	4/6	0.23	6.8	VRE sepsis, candida sepsis	N/A	N/A	Died day 7 - sepsis
		UC2	4/6
	12	Double UC1	4/6	0.16	ND	VRE sepsis	Gr I-II gut	-	Rejected, retransplanted, died day 295.
		UC2	4/6	0.57	ND
Haplo
	13	BM	5/10	4.2	43.2	ARDS	N/A	N/A	Died day 1 - ARDS
	14	BM	7/10	6	55	Aeromonas sp. gastroenteritis	Gr I Skin		Alive 8m

Abbreviations: PBSC: Peripheral Blood Stem Cells; BM: bone marrow; CRBI: catheter related blood stream infection; IFI: invasive fungal infection; BSI: bloodstream infection; VRE: Vancomycin resistant enterococcus; FN: Febrile Neutropenia; N/A: not applicable as patient died early post transplant; ND: not done; ARDS: acute respiratory distress syndrome; UC: Umbilical Cord.

^*According to NIH Criteria for Severity