Figure 3.
Response of WT and BK5.EP4 mice to a single treatment with 400 μg DMBA. A. Macroscopic appearance of dorsal area of treated WT and BK5.EP4 mice. B. Representative histology of H&E stained skin sections of WT (n = 3) mice 48 h after treatment with acetone or DMBA. C. Representative histology of H&E stained skin sections of BK5.EP4 (n = 3) mice 48 h after treatment with acetone or DMBA. D. Carcinoma multiplicity of WT (n = 11) and BK5.EP4 (n = 13) mice after a single treatment with DMBA.