Skip to main content
. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Gastroenterology. 2014 Aug 7;147(6):1238–1254. doi: 10.1053/j.gastro.2014.07.055

Figure 2.

Figure 2

Histologic findings in EoE (40x images). (A) Mucosal biopsy of the esophagus showing a marked eosinophilic infiltrate. Additional findings of note include eosinophil degranulation (white asteric), which often indicates eosinophil activation; eosinophil microabscesses, defined as clusters of at least 4 eosinophils and superficial layering with sloughing of the apical epithelial cells (arrow); and basal cell hyperplasia, frequently occupying 50% or more of the epithelium, with spongiosis, a result of dilated intracellular spaces reflecting leaky mucosal barrier (black bar). (B) In addition to the eosinophilic infiltrate and degranulation (white asterisk), this specimen shows lamina propria fibrosis (black bracket).