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Plasma buprenorphine concentration (mean ± SEM) compared with time after a single administration of (A) 0.02 mg/kg IV buprenorphine (n = 5), (B) 0.18 mg/kg SC SRB (n = 5 for time points 0–224 h, n = 2 for 336 h), and (C) 30 µg/h topical TDB (n = 4) in female Göttingen minipigs.
