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. 2014 Nov 28;11:106. doi: 10.1186/s12977-014-0106-8

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© Etemad et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The HIV RNA+/ Ab- compared to the chronic envelopes have greater sensitivity to interferon- α. Scatter plots show % interferon resistance (replication in the presence as compared to the absence of IFN- α) in CD4+ T cells from 4 different HIV-1 seronegative donors (A – D). Similar to Figure 2, in the early and chronic group unique symbols are used to show the longitudinal changes within an injection drug user. In each scatterplot, the lines denote the median. Significant differences (p ≤0.05) are indicated with a star in the graphs. Symbols in gray denote virus stocks shown to be able to utilize the CXCR4 receptor.