Figure 4.

Convection-enhanced delivery of AuNPs. (A): Before injection; (B): 20 minutes into injection; (C): 24 hours after injection of lipoic acid AuNPs (B,C) which remain confined to the tumor region. (D): 24 hours after injection of PEG-AuNPs which do not remain confined to the tumor region. (E): Red color of 15 nm AuNPs. (F): Treated mouse leg 250 days later.