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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Thromb Res. 2014 Sep 6;134(5):1123–1129. doi: 10.1016/j.thromres.2014.08.024

Table 3.

Interaction of Sulfated LMWLs and Heparin with Thrombin Using PABA Probesa

Ligand
KD(μM)b
ΔF MAX b
CDS03 3.33 ± 0.12 −1.16 ± 0.01
FDS03 5.95 ± 0.44 −1.20 ± 0.04
SDS03 3.36 ± 0.11 −1.07 ± 0.01
UFH 1.74 ± 0.21 −0.34 ± 0.01
a

KD and ΔFMAX values of LMWLs and heparin were measured as described in Experimental Procedures. PABA reversibly binds to the active site of thrombin.

b

Error represents ±1 SE.