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Interaction of Sulfated LMWLs and Heparin with Dansyl labeled Thrombina
| Ligand | KD(nM)b | ΔF MAX b |
|---|---|---|
| CDS03 | 601 ± 122 | −0.71 ± 0.05 |
| FDS03 | 919 ± 77 | −0.54 ± 0.02 |
| SDS03 | 130 ± 29 | −0.16 ± 0.01 |
| UFH | No interaction detected | |
KD and ΔFMAX values of LMWLs and heparin were measured as described in Experimental Procedures. Ser 195 is the active site amino acid labeled by the dansyl probe.
Error represents ±1 SE.
