Table 2.
Clinically significant toxicities (CTCAE v4.3 grades 2–4) encountered (n=22 patients)
| Toxicity | Grade 2 | Grade 3 | Grade 4 | Total (2–4) |
|---|---|---|---|---|
| Rash | 4 | 4 | 0 | 8 |
| Diarrhea | 6 | 1 | 0 | 7 |
| Anemia | 1 | 5 | 0 | 6 |
| Nausea | 4 | 1 | 0 | 5 |
| Thrombocytopenia | 3 | 2 | 0 | 5 |
| Weight loss | 3 | 2 | 0 | 5 |
| Abdominal pain | 1 | 3 | 0 | 4 |
| Hypertension | 1 | 3 | 0 | 4 |
| Anorexia | 3 | 0 | 0 | 3 |
| Arthralgia/Myalgias | 4 | 1 | 0 | 3 |
| Fatigue | 3 | 0 | 0 | 3 |
| Leukopenia | 1 | 1 | 1 | 3 |
| Transaminitis | 2 | 1 | 0 | 3 |
| Dyspnea | 2 | 0 | 0 | 2 |
| Hand-Foot | 2 | 0 | 0 | 2 |
| Headache | 1 | 1 | 0 | 2 |
| Sensory neuropathy | 2 | 0 | 0 | 2 |
| Pericardial effusion | 0 | 0 | 1 | 1 |
| Vomiting | 1 | 0 | 0 | 1 |