Table 2.
Body weight, serum Ca and P, serum PTH, and markers of bone turnover.
| Young | Aged | Two-way ANOVA1 | |||
|---|---|---|---|---|---|
| Control | High P | Control | High P | ||
| Initial body weight (g) | 44.10 ± 0.79A | 44.20 ± 0.65A | 52.71 ± 2.17B | 53.84 ± 2.56B | A |
| Final body weight (g) | 48.66 ± 1.43 | 46.18 ± 0.67 | 51.47 ± 2.28 | 50.69 ± 2.19 | |
| Serum Ca (mg/dL) | 9.15 ± 0.17 | 8.67 ± 0.20 | 8.81 ± 0.27 | 8.60 ± 0.12 | |
| Serum P (mg/dL) | 9.23 ± 0.41 | 9.49 ± 0.47 | 9.07 ± 0.68 | 9.08 ± 0.60 | |
| Serum PTH (pg/mL) | 52.8 ± 12.5A | 181.4 ± 33.0B | 76.7 ± 13.8A | 306.1 ± 51.1C | P, A |
| Serum OC (ng/mL) | 26.58 ± 0.83A | 37.53 ± 2.94B | 7.31 ± 0.48C | 13.44 ± 0.78D | P, A |
| Urine CTx (μg/mmol creatinine) | 5.98 ± 0.91A | 16.73 ± 1.22B | 5.62 ± 1.02A | 9.61 ± 1.13C | P, A, P × A |
The data indicate the mean ± SEM of 6 mice.
A,B,C,DThe different superscript letters denote significant differences (P < 0.05).
1Significant effect (P < 0.05): P = effect of high P diet; A = effect of age; P × A = effect of interaction.