Table 1.
Characteristics of control, nSTZ-PD, and nSTZ-D group rats.
Parameter/group | Control (n = 7) | nSTZ-PD (n = 16) | nSTZ-D (n = 7) |
---|---|---|---|
Food intake (g/day/rat) | 20.69 ± 2.21 | 19.08 ± 1.84 | 26.05 ± 4.68# |
Body weight (g/rat) | 448 ± 40.39 | 394 ± 47.36 | 364 ± 86.00* |
HOMA-IR | 0.740 ± 0.218 | 0.376 ± 0.243* | 0.582 ± 0.176 |
Glucose AUC (mmol/h) | 8.84 ± 0.85 | 28.40 ± 2.98* | 36.38 ± 4.18∗# |
Insulin AUC (μmol/h) | 69.25 ± 13.07 | 40.45 ± 9.96* | 40.61 ± 8.98* |
Glucose AUC/insulin AUC | 0.130 ± 0.015 | 0.744 ± 0.269* | 0.944 ± 0.315* |
Values are expressed as mean ± SD. The asterisk denotes that data are significantly different from control group and the hash mark denotes that data are significantly different from nSTZ-PD group.