Table 1.

Gene-based association analysis in neuroblastoma GWAS dataset (2101 cases and 4202 controls)

GENE SETS	NSNP	NSIG	ISIG	EMP	FDR	SNPs
EEF1A1	4	0	0	1	1	NS
EEF2	6	0	0	1	1	NS
GNB2	3	0	0	1	1	NS
NEFL	8	4	2	0.0076	0.0304	rs118727|rs169061
PCNA	6	0	0	1	1	NS
PRDX2	2	0	0	1	1	NS
SCG2	7	1	1	0.0037	0.0296	rs4673067
VBP1	0	0	0	1	1	NS

NSNP: Number of SNPs in gene and surrounding genomic region (+/− 20Kb)

NSIG: Total number of SNPs below p-value threshold

ISIG: Number of significant also passing LD-criterion

EMP: Empirical gene-based p-value

NS: not significant

FDR: False discovery rate correction method applied to EMP.