Skip to main content
. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Virology. 2014 Aug 20;0:57–62. doi: 10.1016/j.virol.2014.07.052

Fig. 3. The apoptosis mechanism is targeted by the Py-miRNA in infected mice.

Fig. 3

Kidneys were harvested from C3H/BiDa mice neonatally-infected with LID Py or mutant, non-miRNA expressing LID-dl1013 Py at day 8 post injection. Kidney sections were subjected to apoptosis analyses (TUNEL) with the apoptosis marker anti-digoxigenin (red) and anti-polyoma large T antigen (green) antibodies. A. Representative images of kidney stains from each group. An uninfected kidney sample is shown as a control. B. Quantification of apoptosis rates in the LID and LID-dl1013 infected groups. The percentage of cells that double-stained for apoptosis and Py-infection were quantified between the two groups. Roughly 3,000 infected cells from each group were counted and are plotted (** p-value < 0.01).