TABLE 2.
Antibody and T-cell responses
Study Group | Subject ID | HBsAb titer (mIU/mL) | T-cell index Post 3rd dose | |||
---|---|---|---|---|---|---|
Baseline | Post 1st dose | Post 2nd dose | Post 3rd dose | |||
HBsAg alone | #101 | 0 | 0 | 0 | 4.1 | 5.1 |
#102 | 0 | 0 | 0.1 | 1.0 | 1.1 | |
#103 | 0.1 | 0 | 0 | 3.9 | 1.2 | |
#104 | 0 | 0 | 0 | 5.9 | 1.1 | |
#105 | 5.8 | 7.9 | 9.3 | 12.4 | 1.2 | |
HBsAg + Advax 5mg | #206 | 0 | 0 | 4.6 | 33.7 | 2.5 |
#207 | 0 | 0.2 | 23.9 | 177 | 11.9 | |
#208 | 0.7 | 0.6 | 3.8 | 30.7 | 1.7 | |
#209 | 0 | 0 | 3.5 | 46.0 | 1.3 | |
#210 | 0 | 0 | 5.8 | 94.3 | 3.1 | |
#211 | 0 | 0 | 1 | 5.7 | 2.3 | |
HBsAg + Advax 10mg | #312 | 0 | 0 | 0.2 | 9.3 | 7.9 |
#313 | 0.1 | 2 | 2.4 | 42.0 | 8.8 | |
#314 | 0.1 | 0.4 | 6.4 | 49.3 | 8.9 | |
#315 | 0 | 0.1 | 5.1 | 49.7 | 3.6 | |
#316 | 0 | 0.1 | 38.1 | 381.8 | 0.9 |