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. 2014 Nov 18;13:434. doi: 10.1186/1475-2875-13-434

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© Kastner et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Pharmacological characterization of AgOAR45B mutants. A. Dose response curves of optopamine E161Q (closed triangles), E161A (open triangles), D100N (closed squares), D100A (open squares), D100N/E161Q (closed diamonds), and D100A/E161A (open diamonds) double mutants. B. Dose response curves of optopamine S206A (closed boxes), S210A (closed triangles) and S206A/S210A double mutants (open circles). The same control wild-type AgOAR45B (closed circles) data is presented in both A and B. Data are expressed as % 1 μM octopamine response. Means ± SD of three independent experiments are presented.