Table 2.
HbA 1c , body weight and hypoglycaemia in insulin-naïve and insulin-experienced patients, and in the total cohort
| Insulin-experienced, N = 1,966 | Insulin-naïve, N = 6,612 | Total cohort, N = 8,578 | ||
|---|---|---|---|---|
| HbA1c (%) | N | 1056 | 3386 | 4442 |
| Baseline | 9.1 (2.3) | 9.6 (2.2) | 9.5 (2.3) | |
| Week 24 | 7.0 (1.1) | 7.0 (1.0) | 7.0 (1.0) | |
| Change | -2.0 (2.2) | -2.7 (2.2) | -2.5 (2.2) | |
| P value | <0.001 | <0.001 | <0.001 | |
| Body weight (kg) | N | 1459 | 4600 | 6059 |
| Baseline | 68.7 (11.2) | 68.5 (11.3) | 68.5 (11.3) | |
| Week 24 | 69.2 (10.9) | 68.8 (10.8) | 68.9 (10.8) | |
| Change | 0.5 (3.0) | 0.3 (3.1) | 0.3 (3.1) | |
| P value | <0.001 | <0.001 | <0.001 | |
| Overall hypoglycaemia (events/patient year) | N | 1966 | 6612 | 8578 |
| Baseline | 6.12 | 1.2 | 2.32 | |
| Week 24 | 2.14 | 1.37 | 1.54 | |
| Nocturnal hypoglycaemia (events/patient year) | N | 1966 | 6612 | 8578 |
| Baseline | 1.65 | 0.26 | 0.58 | |
| Week 24 | 0.42 | 0.24 | 0.28 | |
| Major hypoglycaemia (events/patient year) | N | 1966 | 6612 | 8578 |
| Baseline | 0.37 | 0.09 | 0.15 | |
| Week 24 | 0.00 | 0.00 | 0.00 | |
| Minor hypoglycaemia (events/patient year) | N | 1966 | 6612 | 8578 |
| Baseline | 5.75 | 1.10 | 2.17 | |
| Week 24 | 2.14 | 1.37 | 1.54 |
Data are mean (sd), n or incidence.